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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">brhejo</journal-id><journal-title-group><journal-title xml:lang="en">The BRICS Health Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>The BRICS Health Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">3034-4700</issn><issn pub-type="epub">3034-4719</issn><publisher><publisher-name>Sechenov University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47093/3034-4700.2025.2.3.27-40</article-id><article-id custom-type="elpub" pub-id-type="custom">brhejo-54</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Brazil–China relations in health: historical context, industrial challenges, and future opportunities</article-title><trans-title-group xml:lang="ru"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2558-6602</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Pinheiro dos Santos</surname><given-names>Wellington</given-names></name></name-alternatives><bio xml:lang="en"><p>Wellington Pinheiro dos Santos, PhD, Professor, Department of Biomedical Engineering, Center for Technology and Geosciences</p><p>Av. da Arquitetura, SN, Cidade Universitária, Recife, Pernambuco, 50740-550</p></bio><email xlink:type="simple">wellington.santos@ufpe.br</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-2262-0575</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Menezes de Carvalho</surname><given-names>Evandro</given-names></name></name-alternatives><bio xml:lang="en"><p>Evandro Menezes de Carvalho, PhD, Professor Getúlio Vargas Foundation</p><p>Botafogo Beach, 190, 7th floor, Botafogo, Rio de Janeiro 22250-145</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9725-8862</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Sobrinho</surname><given-names>Luiz Vianna</given-names></name></name-alternatives><bio xml:lang="en"><p>Luiz Vianna Sobrinho, PhD, Researcher, Faculty of Medicine of Bahia</p><p>Av. Reitor Miguel Calmon, SN, Vale do Canela, Salvador, Bahia, 40110-100</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0071-4850</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Paschoalotte</surname><given-names>Leandro Modolo</given-names></name></name-alternatives><bio xml:lang="en"><p>Leandro Modolo Paschoalotte, PhD, Researcher</p><p>Campinas, Zeferino Vaz University City, Barão Geraldo, Campinas, São Paulo,13083-970</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6482-5840</contrib-id><name-alternatives><name name-style="western" xml:lang="en"><surname>Bittencourt</surname><given-names>Roberto José</given-names></name></name-alternatives><bio xml:lang="en"><p>Roberto José Bittencourt, Professor</p><p>Ceilândia, Brasília, Brazil, 71966-700 </p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>Federal University of Pernambuco</institution><country>Brazil</country></aff><aff xml:lang="en" id="aff-2"><institution>Getúlio Vargas Foundation</institution><country>Brazil</country></aff><aff xml:lang="en" id="aff-3"><institution>Federal University of Bahia</institution><country>Brazil</country></aff><aff xml:lang="en" id="aff-4"><institution>State University of Campinas</institution><country>Brazil</country></aff><aff xml:lang="en" id="aff-5"><institution>Medical School; Catholic University of Brasília</institution><country>Brazil</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2025</year></pub-date><volume>2</volume><issue>3</issue><elocation-id>27–40</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Pinheiro dos Santos W., Menezes de Carvalho E., Sobrinho L., Paschoalotte L., Bittencourt R., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Pinheiro dos Santos W., Menezes de Carvalho E., Sobrinho L., Paschoalotte L., Bittencourt R.</copyright-holder><copyright-holder xml:lang="en">Pinheiro dos Santos W., Menezes de Carvalho E., Sobrinho L., Paschoalotte L., Bittencourt R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.bricshealthjournal.com/jour/article/view/54">https://www.bricshealthjournal.com/jour/article/view/54</self-uri><abstract><p>This article analyzes the evolving health cooperation between Brazil and China as a strategic frontier in South-South collaboration. At a time of global health insecurity and technological inequality, the partnership between these two continental powers offers a transformative alternative to traditional donor-recipient models. The analysis traces a shift from commodity-based trade to a potential alliance in co-innovation, encompassing vaccines, artificial intelligence, biotechnology, and digital health. Brazil’s deep dependency on imported medical inputs and its fragmented industrial base stand in contrast to China’s stateled model of technological scaling and global health outreach. Yet, this asymmetry also reveals opportunities: Brazil’s universal health system, research institutions, and regional leadership can be aligned with China’s production capacity, digital infrastructure, and development finance to build shared technological sovereignty. The paper examines how Brazil’s renewed industrial policy under Lula’s administration opens new pathways for joint research and development, regional pharmaceutical production, and equitable technology transfer. It also confronts persistent challenges – technological imbalances, intellectual property constraints, institutional volatility, and geopolitical pressures aimed at curtailing South-South alignment. A successful partnership, the article argues, must be grounded in transparent governance, mutual benefit, and a commitment to health as a public good. It concludes with a proposal for a decentralized health innovation ecosystem in Brazil, inspired by China’s special economic zones, to overcome the historical concentration of technological power and promote equitable development across the North, Northeast, and Center-West. In doing so, the Brazil–China relationship can become a model for a more just, resilient, and multipolar global health order.</p></abstract><kwd-group xml:lang="en"><kwd>Brazil–China relations</kwd><kwd>global health diplomacy</kwd><kwd>health industrial policy</kwd><kwd>South-South cooperation</kwd><kwd>technological sovereignty</kwd><kwd>geopolitical economy of health</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The authors are grateful to the Brazilian research agency Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq, for the partial support of this work.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Augusto PDVB, Macedo FGC, Sousa CET, Barbosa FM, Sanson MZ, Guanabarino MA, Borges FT. A atenção primária em saúde brasileira é para pobres? In: Borges FT, ed. 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