Transforming cancer care in emerging economies: India’s AI innovation
https://doi.org/10.47093/3034-4700.2026.3.2.103
Abstract
Cancer remains a major public health challenge across BRICS member countries. Together, these countries represent more than 40% of the global population and account for approximately 9.0 million new cancer cases and 4.66 million cancer deaths. This review aims to summarize cancer epidemiology across the 11 BRICS member countries, with emphasis on breast and ovarian cancers, describe India’s cancer-control and digital-health architecture, and assess the evidence and translational potential of iOncology.ai. Cancer patterns and access to screening, early diagnosis, and specialist oncology care vary across member countries. Breast cancer is among the leading malignancies affecting women and is the leading female cancer in most BRICS countries. Ovarian cancer is less common but is frequently diagnosed at advanced stages and is associated with poor outcomes. In India, cancer-control activities are delivered through the National Health Mission, the National Programme for Prevention and Control of Non-Communicable Diseases, and complementary surveillance, population-based screening, tertiary-care, and financial-protection mechanisms. The Viksit Bharat 2047 vision and Digital India programme provide a policy context for digital health development, including the Ayushman Bharat Digital Mission. Within this ecosystem, iOncology.ai is an national artificial-intelligence platform undergoing pilot-stage clinical validation and implementation evaluation. The review also identifies priorities for collaborative digital oncology in the context of India’s BRICS Chairship in 2026.
Keywords
About the Authors
Ashok SharmaIndia
Ashok Sharma, PhD, Professor
New Delhi, 110029, India
Alisha Behera
India
Alisha Behera, MSc, SRF
New Delhi, 110029, India
Sahar Qazi
India
Sahar Qazi, PhD, Scientist-B
New Delhi, 110029, India
Samanvaya Gupta
India
Samanvaya Gupta, BTech Student, Computer Science with specialization in Artificial Intelligence
New Delhi, 110078, India
Ekta Dhamija
India
Ekta Dhamija, MD, Professor
New Delhi, 110029, India
Rambha Pandey
India
Rambha Pandey, MD, Professor
New Delhi, 110029, India
Kunhi Parambath Haresh
India
Kunhi Parambath Haresh, MD, Professor
New Delhi, 110029, India
Lakshmy Panat
India
Lakshmi Panat, BE, Scientist G
Pune, Maharashtra, 411007, India
Yenishetti Swapna
India
Yenishetti Swapna, BTech, Scientist E
Pune, Maharashtra, 411007, India
Babita Kataria
India
Babita Kataria, DM, Assistant Professor
Jhajjar Campus, Haryana, AIIMS, New Delhi, 124105, India
Jyoti Sharma
India
Jyoti Sharma, MCh, Associate Professor
Jhajjar Campus, Haryana, AIIMS, New Delhi, 124105, India
Aarthi S. Jayraj
India
Aarthi S Jayraj, MCh, Assistant Professor
Jhajjar Campus, Haryana, AIIMS, New Delhi, 124105, India
Karun Kamboj
India
Karun Kamboj, MD, Assistant Professor
Jhajjar Campus, Haryana, AIIMS, New Delhi, 124105, India
M. D. Ray
India
M.D Ray, MD, PhD, Professor
New Delhi, 110029, India
Sachin Khurana
India
Sachin Khurana, MD, Professor
New Delhi, 110029, India
Atul Batra
India
Atul Batra, MD, Professor
New Delhi, 110029, India
Ashutosh Mishra
India
Ashutosh Mishra, MCh, Additional Professor
New Delhi, 110029, India
Fouzia Siraj
India
Fouzia Siraj, MD, Scientist E and In-charge of the Pathology Lab
New Delhi, 110029, India
Arun Kumar
India
Arun Kumar, PhD, Senior Scientist
Patna, Bihar, 801505, India
Jai Bhagwan Sharma
India
Jai Bhagwan Sharma, MD, PhD, Professor
New Delhi, 110029, India
Shyam S. Chauhan
India
Shyam S. Chauhan, PhD, Professor and ICMR-Dr A.S. Paintal Distinguished Scientist Chair
New Delhi, 110029, India
Gaura Kishor Rath
India
Gaura Kishor Rath, MD, DSc, Professor
New Delhi, 110029, India
References
1. Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever-increasing importance of cancer as a leading cause of premature death worldwide. Cancer. 2021;127(16):3029-3030. doi:10.1002/cncr.33587
2. Sung H, Filho AM, Laversanne M, et al. Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 34 cancers in 186 countries. CA Cancer J Clin. 2026;76(4):e70090. doi:10.3322/caac.70090
3. Goss PE, Strasser-Weippl K, Lee-Bychkovsky BL, et al. Challenges to effective cancer control in China, India, and Russia. Lancet Oncol. 2014;15(5):489-538. doi:10.1016/S1470-2045(14)70029-4
4. Soerjomataram I, Bray F. Planning for tomorrow: global cancer incidence and the role of prevention 2020–2070. Nat Rev Clin Oncol. 2021;18(10):663-672. doi:10.1038/s41571-021-00514-z
5. Pramesh CS, Badwe RA, Bhoo-Pathy N, et al. Priorities for cancer research in low- and middle-income countries: a global perspective. Nat Med. 2022;28(4):649-657. doi:10.1038/s41591-022-01738-x
6. Mallath MK, Taylor DG, Badwe RA, et al. The growing burden of cancer in India: epidemiology and social context. Lancet Oncol. 2014;15(6):e205-e212. doi:10.1016/S1470-2045(14)70115-9
7. Nath A, Taneja R, Thadi YS, Sarveswaran G, Mathur P. A comparative study of incidence, mortality and disability adjusted life years (DALYs) for leading cancers in BRICS countries. ecancermedicalscience. 2024;18. doi:10.3332/ecancer.2024.1773
8. Pearce A, Sharp L, Hanly P, et al. Productivity losses due to premature mortality from cancer in Brazil, Russia, India, China, and South Africa (BRICS): A population-based comparison. Cancer Epidemiol. 2018;53:27-34. doi:10.1016/j.canep.2017.12.013
9. Cravo Neto DB, Santini De Oliveira M, Santos SLDX, et al. The BRICS Partnership for the Elimination of Socially Determined Diseases: a multilateral agenda to health equity. BRICS Health J. 2025;2(3):60-71. doi:10.47093/3034-4700.2025.2.3.60-71
10. Oswal K, Gaurav K, Pradhan A, Ramachandran V, Sebastian P, Basu P. Current Status of Implementation of Cancer Screening Programme in India: A Review of Policies and Practice. Asian Pac J Cancer Prev. 2025;26(4):1117-1128. doi:10.31557/APJCP.2025.26.4.1117
11. Debnath S, Pal P, Singh AK, et al. Epidemiological profile of patients with malignant neoplasm admitted to a tertiary care center in India: a retrospective cross-sectional study. Front Oncol. 2025;15:1636807. doi:10.3389/fonc.2025.1636807
12. Topol EJ. High-performance medicine: the convergence of human and artificial intelligence. Nat Med. 2019;25(1):44-56. doi:10.1038/s41591-018-0300-7
13. Rajkomar A, Dean J, Kohane I. Machine learning in medicine. N Engl J Med. 2019;380(14):1347-1358. doi:10.1056/NEJMra1814259
14. Esteva A, Robicquet A, Ramsundar B, et al. A guide to deep learning in healthcare. Nat Med. 2019;25(1):24-29. doi:10.1038/s41591-018-0316-z
15. He J, Baxter SL, Xu J, Xu J, Zhou X, Zhang K. The practical implementation of artificial intelligence technologies in medicine. Nat Med. 2019;25(1):30-36. doi:10.1038/s41591-018-0307-0
16. Jiang F, Jiang Y, Zhi H, et al. Artificial intelligence in healthcare: past, present and future. Stroke Vasc Neurol. 2017;2(4):230-243. doi:10.1136/svn-2017-000101
17. Kelly CJ, Karthikesalingam A, Suleyman M, Corrado G, King D. Key challenges for delivering clinical impact with artificial intelligence. BMC Med. 2019;17(1):195. doi:10.1186/s12916-019-1426-2
18. A Path for Translation of Machine Learning Products into Healthcare Delivery. EMJ Innov. Published online January 27, 2020. doi:10.33590/emjinnov/19-00172
19. Bajwa J, Munir U, Nori A, Williams B. Artificial intelligence in healthcare: transforming the practice of medicine. Future Healthc J. 2021;8(2):e188-e194. doi:10.7861/fhj.2021-0095
20. Campanella G, Hanna MG, Geneslaw L, et al. Clinical-grade computational pathology using weakly supervised deep learning on whole slide images. Nat Med. 2019;25(8):1301-1309. doi:10.1038/s41591-019-0508-1
21. McKinney SM, Sieniek M, Godbole V, et al. International evaluation of an AI system for breast cancer screening. Nature. 2020;577(7788):89-94. doi:10.1038/s41586-019-1799-6
22. Goel I, Bhaskar Y, Kumar N, et al. Role of AI in empowering and redefining the oncology care landscape: perspective from a developing nation. Front Digit Health. 2025;7:1550407. doi:10.3389/fdgth.2025.1550407
23. Meena JK, Yadav K, Mehrotra R. Implementing cancer prevention strategies in India: progress, persistent challenges and future directions. ecancermedicalscience. 2025;19. doi:10.3332/ecancer.2025.2042
24. Mathur P, Sathishkumar K, Chaturvedi M, et al. Cancer Statistics, 2020: Report From National Cancer Registry Programme, India. JCO Glob Oncol. 2020;(6):1063-1075. doi:10.1200/GO.20.00122
25. Narayan A, Bhushan I, Schulman K. India’s evolving digital health strategy. Npj Digit Med. 2024;7(1):284. doi:10.1038/s41746-024-01279-2
26. Kankaria A, Shukla P, Vijayakumar M, et al. Enhancing screening, early diagnosis and treatment initiation of oral, breast and cervical cancer in selected districts of India: an implementation research protocol. BMJ Open. 2026;16(6):e112428. doi:10.1136/bmjopen-2025-112428
27. Smrithi NS, Sumit K, Zubair SM. A qualitative study on users’ perspective on the functioning of the National Non-Communicable disease portal in Dakshina Kannada district, Karnataka. BMC Health Serv Res. 2026;26(1):104. doi:10.1186/s12913-026-14008-0
28. Menon KV, Victor V, Vaidya OS. Does integrating pharmaceutical coverage into publicly financed health insurance reduce out-of-pocket spending? Difference-in-differences evidence from Kerala, India. Soc Sci Med. 2026;404:119483. doi:10.1016/j.socscimed.2026.119483
29. Mukherjee P, Das A, Banerjee A, Mitra K, Das D. A Cross-sectional Study on Awareness and Utilisation of Government Health Insurance Schemes among Patients at a Tertiary Level Hospital in Kolkata, India. J Clin Diagn Res. Published online 2024. doi:10.7860/JCDR/2024/66294.19042
30. Wadasadawala T, Mohanty SK, Sen S, et al. Out-of-pocket payment and financial risk protection for breast cancer treatment: a prospective study from India. Lancet Reg Health – Southeast Asia. 2024;24:100346. doi:10.1016/j.lansea.2023.100346
31. Gangadharam T, Radhika K. Evaluating government health insurance schemes: reducing the cost burden of cancer treatment for vulnerable populations in Andhra Pradesh. Indian Dev Econ Rev. 2025;1(2):165-177. doi:10.47509/IDER.2025.v01i02.04
32. Mahajan H, Reddy N, Devi NGM, et al. Projected cancer burden, challenges, and barriers to cancer prevention and control activities in the state of Telangana. Janardhanan R, ed. PLOS One. 2023;18(7):e0278357. doi:10.1371/journal.pone.0278357
33. S. P, Shastri SG, P. K. S, et al. Road to universal health coverage: unique model of Karnataka, India. Int J Community Med Public Health. 2023;10(5):1947-1954. doi:10.18203/2394-6040.ijcmph20231301
34. Trivedi M, Saxena A, Shroff Z, Sharma M. Experiences and challenges in accessing hospitalization in a government-funded health insurance scheme: Evidence from early implementation of Pradhan Mantri Jan Aarogya Yojana (PM-JAY) in India. Garg CC, ed. PLOS One. 2022;17(5):e0266798. doi:10.1371/journal.pone.0266798
35. Singh S, Rathore M, Raj A. Utilization patterns of Chiranjeevi Swasthya Bima Yojana in Rajasthan during financial year 2023 to 2024: a cross-sectional study at a tertiary care hospital. Int J Community Med Public Health. 2024;11(11):4367-4372. doi:10.18203/2394-6040.ijcmph20243300
36. Thapliyal N, Bassi S, Bahl D, et al. A Scoping Review of Existing Policy Instruments to Tackle Overweight and Obesity in India: Recommendations for a Social and Behaviour Change Communication Strategy. F1000Research. 2024;13:496. doi:10.12688/f1000research.149857.2
37. Dash S, Shakyawar SK, Sharma M, Kaushik S. Big data in healthcare: management, analysis and future prospects. J Big Data. 2019;6(1):54. doi:10.1186/s40537-019-0217-0
38. Kvedar JC, Fogel AL, Elenko E, Zohar D. Digital medicine’s march on chronic disease. Nat Biotechnol. 2016;34(3):239-246. doi:10.1038/nbt.3495
39. Bhattacharya S, Gopal KM, Garg S. Sustaining Current Policies and Introducing New Initiatives: Strategic Five-year Plan for the Government of India. J Epidemiol Found India. 2024;2(3):134-143. doi:10.56450/JEFI.2024.v2i03.010
40. Mishra US, Yadav S, Joe W. The Ayushman Bharat Digital Mission of India: An Assessment. Health Syst Reform. 2024;10(2):2392290. doi:10.1080/23288604.2024.2392290
41. Inampudi S, Rajkumar E, Gopi A, Vany Mol KS, Sruthi KS. Barriers to implementation of digital transformation in the Indian health sector: a systematic review. Humanit Soc Sci Commun. 2024;11(1):632. doi:10.1057/s41599-024-03081-7
42. Bates DW, Wright A. Evaluating eHealth: Undertaking Robust International Cross-Cultural eHealth Research. Sheikh A, ed. PLoS Med. 2009;6(9):e1000105. doi:10.1371/journal.pmed.1000105
43. Lekadir K, Frangi AF, Porras AR, et al. FUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare. BMJ. 2025;388:e081554. doi:10.1136/bmj-2024-081554
Review
For citations:
Sharma A., Behera A., Qazi S., Gupta S., Dhamija E., Pandey R., Haresh K.P., Panat L., Swapna Ye., Kataria B., Sharma J., Jayraj A.S., Kamboj K., Ray M.D., Khurana S., Batra A., Mishra A., Siraj F., Kumar A., Sharma J.B., Chauhan Sh.S., Rath G.K. Transforming cancer care in emerging economies: India’s AI innovation. The BRICS Health Journal. 2026;3(2):49-69. https://doi.org/10.47093/3034-4700.2026.3.2.103
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